The Dictyostelium GSK3 kinase GlkA coordinates signal relay and chemotaxis in response to growth conditions

Developmental Biology, pp. 56-72, 2018.

Cited by: 1|Bibtex|Views13|DOI:https://doi.org/10.1016/j.ydbio.2018.01.007
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Other Links: pubmed.ncbi.nlm.nih.gov|academic.microsoft.com|www.sciencedirect.com

Abstract:

GSK3 plays a central role in orchestrating key biological signaling pathways, including cell migration. Here, we identify GlkA as a GSK3 family kinase with functions that overlap with and are distinct from those of GskA. We show that GlkA, as previously shown for GskA, regulates the cell's cytoskeleton through MyoII assembly and control o...More

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