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The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure.

PLOS GENETICS, no. 5 (2017)

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INT6/eIF3e is a highly conserved component of the translation initiation complex that interacts with both the 26S proteasome and the COP9 signalosome, two complexes implicated in ubiquitin-mediated protein degradation. The INT6 gene was originally identified as the insertion site of the mouse mammary tumor virus (MMTV), and later shown to...更多

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