Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach.

Ines Valenta,Zoltan V Varga,Heather Valentine,Resat Cinar,Andrew Horti,William B Mathews,Robert F Dannals,Kimberley Steele,George Kunos,Richard L Wahl,Martin G Pomper,Dean F Wong,Pal Pacher,Thomas H Schindler

JACC: Cardiovascular Imaging（2018）

引用 25|浏览46

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摘要

Noninvasive imaging of cardiac CB1-R expression in obesity is feasible applying [C]-OMAR and PET/CT. These results may provide a rationale for further clinical testing of CB1-R-targeted molecular imaging in cardiometabolic diseases.

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关键词

anandamide,cannabinoid type 1 receptor,CB1 receptor imaging,[11C]-OMAR,endocannabinoids,heart,obesity,PET/CT,2-arachidonoylglycerol

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