PTEN at the interface of immune tolerance and tumor suppression.

Andrew Brandmaier,Sheng-Qi Hou,Sandra Demaria,Silvia C Formenti,Wen H Shen

Frontiers in biology（2017）

引用 18|浏览2

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摘要

Rational design of personalized anti-cancer treatment requires mechanistic understanding of diverse PTEN signaling pathways in modulation of the crosstalk between tumor and immune cells.

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关键词

PTEN,epigenome,genome,metabolism,phosphoinositide 3-kinase,regulatory T cells

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