[Antimicrobial susceptibility and drug-resistance genes of Yersinia spp. of retailed poultry in 4 provinces of China].

Z X Peng, M Y Zou,J Xu, W Y Guan,Y Li, D R Liu, S S Zhang,Q Hao, S F Yan, W Wang, D M Yu, F Q Li

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine](2018)

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摘要
To monitor the antimicrobial resistance and drug-resistance genes of , and recovered from retailed fresh poultry of 4 provinces of China. The susceptibility of 25 isolated spp. to 14 classes and 25 kinds of antibiotics was determined by broth microdilution method according to CLSI (Clinical and Laboratory Standards Institute). The antibiotic resistance genes were predicted with antibiotic resistance genes database (ARDB) using whole genome sequences of spp. In all 22 tested, 63.7% (14 isolates), 22.8% (5 isolates), 4.6% and 4.6% of 1 isolates exhibited the resistance to cefoxitin, ampicillin-sulbactam, nitrofurantoin and trimethoprim-sulfamethoxazole, respectively. All the 25 isolates were multi-drug resistant to more than 3 antibiotics, while 64.0% of isolates were resistant to more than 4 antibiotics. A few isolates of this study were intermediate to ceftriaxone and ciprofloxacin. Most spp. isolates contained antibiotic resistance genes and , and 5 isolates recovered from fresh chicken also contained 1, 2 and 3. The multi-drug resistant spp. isolated from retailed fresh poultry is very serious in the 4 provinces of China, and their contained many kinds of drug-resistance genes.
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关键词
Drug resistance,Drug resistance gene,Yersinia enterocolitica
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