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The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.

The Journal of biological chemistry, (2018)

Cited by: 2|Views6
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Abstract

Connexin 43 (Cx43, also known as GJA1), is the most ubiquitously expressed connexin isoform in mammalian tissues. It forms intercellular gap junction (GJ) channels, enabling adjacent cells to communicate both electrically and metabolically. Cx43 is a short-lived protein which can be quickly degraded by the ubiquitin-dependent proteasomal,...More

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Author
Jian Sun
Jian Sun
Qianwen Hu
Qianwen Hu
Liheng Zhou
Liheng Zhou
Jinsong Lu
Jinsong Lu
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