Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies.

Mercedes Rubio,Jose Luis Maestro,Maria-Dolors Piulachs,Xavier Belles

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms（2018）

引用 13|浏览21

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摘要

•Argonaute (Ago) proteins are key in RNA silencing.•Ago1 and Ago2 are respectively associated with miRNA and siRNA pathways in Drosophila.•Blattella preferentially uses Ago1 and Ago2 in miRNA and siRNA pathways, respectively.•These associations have been evolutionary conserved from cockroaches to flies.

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关键词

Argonaute proteins,RNAi,miRNA,siRNA,Blattella,Drosophila

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