GOLPH3 Promotes Glioma Progression Via Facilitating JAK2–STAT3 Pathway Activation

Shishuang Wu,Jiale Fu,Yu Dong,Qinghao Yi,Dong Lu,Weibing Wang,Yanhua Qi,Rutong Yu,Xiuping Zhou

Journal of neuro-oncology（2018）

引用 28|浏览4

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摘要

Our recent work reported that GOLPH3 promotes glioma progression via inhibiting endocytosis and degradation of EGFR. The current study aimed to explore the potential regulating mechanism of GOLPH3 on JAK2–STAT3 signaling, a downstream effector of EGFR, in glioma progression.

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关键词

Glioma,GOLPH3,JAK2,STAT3,Proliferation

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