Effectiveness of Mild Moxibustion for Sub-Health Conditions in Pre- and Post-Menopausal Women: A Randomized Controlled Clinical Trial.

Background: Mild moxibustion has been reported to effectively treat menopausal syndrome. This study investigated the efficacy and safety of using mild moxibustion at Shenshu for treating sub-health states in perimenopausal women. Material/Methods: Sixty participants were randomly assigned to moxibustion and control groups. Participants in the moxibustion group received mild moxibustion at bilateral Shenshu (BL23) for 15 min daily. A course was 5 days, with 2 days between courses; treatment was conducted for 4 courses. Participants in the control group were given vitamin E soft capsules for 28 days. Physical condition, living conditions, emotional status, and energy status scores were assessed, and serum sex hormone levels measured. Results: Mild moxibustion significantly improved physical condition, living conditions, and emotional status compared to the control group after treatment (P<0.05). Physical condition (P<0.01) and living conditions (P<0.05) improved significantly in post-menopausal women, while living conditions and emotional status were improved in pre-menopausal women (P<0.05). Serum estradiol level was significantly higher after moxibustion, especially for pre-menopausal women (P<0.01). Conclusions: Mild moxibustion is safe and effective for treating sub-health state in pre-menopausal and post-menopausal women. A study with larger sample size and longer-term treatment is needed for further assessment of this topic.