RNF213 p.R4810K Polymorphism and the Risk of Moyamoya Disease, Intracranial Major Artery Stenosis/Occlusion, and Quasi-Moyamoya Disease: A Meta-Analysis.

Yue Wang,Michael Mambiya,Qian Li,Luping Yang, He Jia,Yibo Han,Wanyang Liu

Journal of Stroke and Cerebrovascular Diseases（2018）

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摘要

RNF213 p.R4810K was associated with MMD, ICASO, and quasi-MMD in different genetic models. Subgroup analysis indicated highly significantly higher risk in the Japanese patients. However, further well-designed studies with larger sample size and comprehensive data are needed to confirm our findings and provide a profound conclusion.

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关键词

Ring finger protein 213,p.R4810K,moyamoya disease,intracranial major artery stenosis/occlusion,quasi-moyamoya disease

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