“Tuberculosis in Advanced HIV Infection is Associated with Increased Expression of IFNγ and Its Downstream Targets”
BMC Infectious Diseases(2018)
摘要
Tuberculosis (TB) is the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging particularly when HIV infection is advanced. Several gene signatures and serum protein biomarkers have been identified that distinguish active TB from latent infection. Our study was designed to assess if gene expression signatures and cytokine levels would distinguish active TB in advanced HIV.
更多查看译文
关键词
Tuberculosis,HIV,Biomarker,TLR,Inflammation,IRIS,Transcriptomics,Cytokines,CXCL10,IFNγ,FcGR1A,BATF2
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要