Safety and immunogenicity of a Vi-DT typhoid conjugate vaccine: Phase I trial in Healthy Filipino adults and children.

Vaccine（2018）

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摘要

•Vi-DT is safe and well tolerated in participants aged 2–45 years.•Significantly higher immune responses post Vi-DT compared to Vi polysaccharide vaccine.•No further increase in GMT post second dose as compared to post first dose of Vi-DT.

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关键词

Typhoid,Conjugate vaccine,Vi-DT,Safety,Immunogenicity,The Philippines

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