Immunosuppressive regimen and risk for de novo malignancies after liver transplantation for alcoholic liver disease.

•Alcoholic liver disease is the main indication for liver transplantation in France and one of the main indications worldwide.•De novo malignancies after liver transplantation for alcoholic liver disease is a frequent and life-threatening long-term complication.•The main risk factor for de novo malignancies after liver transplantation for alcoholic liver disease is tobacco smoking (both past and active).•Using mTOR inhibitor-based immunosuppressive regimen could reduce this risk for de novo malignancies after liver transplantation for alcoholic liver disease.