Too sweet to resist: Control of immune cell function by O-GlcNAcylation.

Tristan de Jesus,Sudhanshu Shukla,Parameswaran Ramakrishnan

Cellular Immunology（2018）

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摘要

•O-GlcNAcylation of cytoplasmic and nuclear proteins in immune cells regulates immune response.•O-GlcNAcylation acts as a connecting link between metabolism and immunity.•Targeting O-GlcNAcylation-dependent immune cell signaling may prove effective in treating immune disorders.

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关键词

GlcNAc,HBP,NF-κB,NFAT,O-GlcNAc,OGA,OGT,PUGNAc

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