Community-based comprehensive measures to prevent severe fever with thrombocytopenia syndrome, China

•A feasible solution for the control of severe fever with thrombocytopenia syndrome is presented, which was deployed in some rural villages in China.•The comprehensive measures, which included health education and risk communication, weed removal, livestock management, and tick control, were performed and evaluated.•Based on the above strategy and the practice in pilot areas, the actual numbers of cases and of infected villages were obviously lower than the values predicted in time-series models using per-month data from previous years.