Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus musculus).

Journal of Hazardous Materials(2018)

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摘要
•Co-exposure to MPs and OPFRs induced greater oxidative stress in mice.•Co-exposure to MPs and OPFRs induced greater neurotoxicity in mice.•Co-exposure to MPs and OPFRs enhanced disruption of amino acid metabolism and energy metabolism in mice.
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关键词
Microplastics,Organophosphorus flame retardants,Co-exposure,Metabolomics,Environmental health
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