Ibrutinib as salvage therapy in mantle cell lymphoma with central nervous system involvement in a pretreated unfit patient.

Orsola Vitagliano,Fabio Trastulli,Fabiana Cacace,Stefania Leone,Mara Memoli,Giulia Scalia,Marianna Notarangelo,Ciro G Mainolfi,Amalia De Renzo,Fabrizio Pane

LEUKEMIA & LYMPHOMA（2018）

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摘要

Mantle cell lymphoma (MCL) accounts for approximately 3–6% of all Non-Hodgkin Lymphomas (NHL). Patients’ median age at diagnosis is 68 years [1] with male predominance and median survival of 4–5 ye...

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mantle cell lymphoma,central nervous system involvement

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