Full spectroscopic characterization of two crystal pseudopolymorphic forms of the antiandrogen cortexolone 17α-propionate for topic application.

Patrizia Ferraboschi, Maria Chiara Sala,Riccardo Stradi,Laura Ragonesi, Clarissa Gagliardi, Paolo Lanzarotti,Enzio M Ragg,Matteo Mori,Fiorella Meneghetti

Steroids（2017）

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摘要

The two solid state forms of the topically active antiandrogen cortexolone-17α-propionate useful in the treatment of skin disorders were fully characterized by several spectroscopic methods for monitoring and controlling pseudopolymorphism.

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关键词

Solvopolymorphism,Steroidal hormone,X-ray diffractometry,Solid-state NMR spectroscopy

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