Chronic Lymphocytic Leukemia: Clinical Stages Maintain Their Prognostic Significance Over the Course of the Disease and Are Surrogates for Response to Therapy.

Eva Puy Vicente,Carolina Cuellar-García, Montserrat Martinez,Alfons Soler,Alba Mora,Rosa Bosch,Salut Brunet,Javier Briones,Irene García,Albert Esquirol,Miquel Granell,Silvana Saavedra,Josep Nomdedeu,Jorge Sierra,Rodrigo Martino,Carol Moreno

Clinical Lymphoma Myeloma and Leukemia（2018）

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摘要

The results of the present study have shown that for patients with CLL, the Binet clinical stages are good outcome predictors throughout the disease course and also suggest that changes in Binet clinical stage could be useful as response surrogates and to divide the IWCLL PR category into different prognostic subgroups.

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关键词

Binet clinical stage,CLL,Downstaging,Heterogeneous outcome,Response assessment

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