Functional Modification of Electrospun Poly(ε-caprolactone) Vascular Grafts with the Fusion Protein VEGF-HGFI Enhanced Vascular Regeneration

Qiuying Zhang
Qiuying Zhang
Liqiang Zhao
Liqiang Zhao
Ting Wang
Ting Wang
Dengke Zhi
Dengke Zhi
Shaoyang Ma
Shaoyang Ma
Peixin Zhang
Peixin Zhang
Siming Zhang
Siming Zhang
Wen Li
Wen Li

ACS applied materials & interfaces, Volume 9, Issue 13, 2017, Pages 11415-11427.

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Abstract:

Synthetic artificial vascular grafts have exhibited low patency rate and severe neointimal hyperplasia in replacing small-caliber arteries (<6 mm) because of their failure to generate a functional endothelium. In this study, small-caliber (2.0 mm) electrospun poly(ε-caprolactone) (PCL) vascular grafts were modified with a fusion protein V...More

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