The involvement of NK1 and Y2 receptor in the development of laser-induced CNVs in C57Bl/6N mice.

Yvonne Nowosielski,Gertrud Haas,Christof Seifarth, Werner Wohlfarter,Ramon Tasan,Michael Verius,Josef Troger,Nikolaos Bechrakis

Experimental Eye Research（2018）

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摘要

•Pathophysiology of age-related macular degeneration is still not fully understood.•NK1 and Y2 receptor knockout mice show smaller laser-induced CNV volumes.•NK1 and Y2 receptors mediate early development of laser-induced CNVs.•OCT and flatmount CNV volumes show strong correlation.

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关键词

Laser-induced CNV,NK1,Y2,Eylea®

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