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SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.

Nature communications, no. 1 (2018): 3157

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Regulatory T (Treg) cells are essential for maintaining immune homeostasis and tolerance, but the mechanisms regulating the stability and function of Treg cells have not been fully elucidated. Here we show SUMO-specific protease 3 (SENP3) is a pivotal regulator of Treg cells that functions by controlling the SUMOylation and nuclear locali...更多

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作者
Yimin Lao
Yimin Lao
Xiao-Lu Teng
Xiao-Lu Teng
Song Li
Song Li
Yan Zhou
Yan Zhou
Feixiang Wang
Feixiang Wang
Xinwei Guo
Xinwei Guo
Siyu Deng
Siyu Deng
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