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Antinociception by Intrathecal Delivery of the Novel Non-Opioid 1-Amino-1-Cyclobutanecarboxylic Acid.

EUROPEAN JOURNAL OF PAIN, no. 2.0 (2019): 260-271

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Abstract

Background Neuraxial opioids are widely used for intraoperative and post-operative analgesia. The risk of severe adverse effects including respiratory depression accompanies this analgesia, prompting the need for effective non-opioid alternatives. Systemic 1-amino-1-cyclobutanecarboxylic acid showed promise in preliminary studies to produ...More

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