Effectiveness of pneumococcal Haemophilus influenzae protein D conjugate vaccine against pneumonia in children: A cluster-randomised trial.

Vaccine(2018)

引用 14|浏览28
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摘要
•First European trial on effectiveness of a PCV against pneumonia in children.•PHiD-CV10 reduced any hospital-diagnosed pneumonia by 27%.•Reduction of pneumonia with alveolar consolidation or pleural effusion by 45%.•Vaccine-preventable incidence of pneumonia considerable for a high-income setting.•We used vaccine as a probe to estimate disease burden.
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关键词
Vaccine effectiveness,Pneumococcus,Clinical trial,Pneumonia,Infant
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