Vinylation of Benzylic Amines via C-N Bond Functionalization of Benzylic Pyridinium Salts.

Cross-couplings of benzylic pyridinium salts and vinylboronic acids or esters have been developed. Via these benzylic pyridinium intermediates, benzylic amines can be engaged in these cross-couplings via C-N bond functionalization. This method boasts mild reaction conditions and excellent tolerance for heteroaryl substituents and a range of functional groups.