Prognostic Value of Early, Conventional Proton Magnetic Resonance Spectroscopy in Cooled Asphyxiated Infants.
BMC Pediatrics(2018)
摘要
Neonatal hypoxic-ischemic encephalopathy (HIE) commonly leads to neurodevelopmental impairment, raising the need for prognostic tools which may guide future therapies in time. Prognostic value of proton MR spectroscopy (H-MRS) between 1 and 46 days of age has been extensively studied; however, the reproducibility and generalizability of these methods are controversial in a general clinical setting. Therefore, we investigated the prognostic performance of conventional H-MRS during first 96 postnatal hours in hypothermia-treated asphyxiated neonates.
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关键词
Perinatal asphyxia,Hypoxic-ischemic encephalopathy,Proton magnetic resonance spectroscopy,Conventional sequence,Neurodevelopmental outcome
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