Evaluation of the pathogenicity of mammalian orthoreovirus type 3 (MRV3) in germ-free gnotobiotic pigs and of the efficacy of an inactivated vaccine against MRV3 infection in neonatal conventional piglets.

Dianjun Cao,Harini Sooryanarain,Danielle M Yugo,Debin Tian,Adam J Rogers,C Lynn Heffron,Athmaram Thimmasandra Narayanappa,Tanya LeRoith,Christopher Overend,Shannon R Matzinger,Subbiah Elankumaran, Joseph R Hermann,Abby R Patterson,Xiang-Jin Meng

Veterinary Microbiology（2018）

引用 4|浏览20

暂无评分

摘要

•Vaccination of sows with an inactivated MRV3 vaccine induced only a low level humoral response.•Maternal immunity acquired from vaccinated sows reduces MRV3 replication.•The U.S. MRV3 infects but only causes very mild diarrhea in pigs.

查看译文

关键词

Mammalian orthoreovirus type 3 (MRV3),Inactivated vaccine,Gnotobiotic pigs,Pregnant sows,Neonatal pigs,Maternal immunity,Pathogenicity

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要