Paracetamol-induced liver injury modelled in Xenopus laevis embryos.

Katy Saide,Victoria Sherwood,Grant N Wheeler

Toxicology Letters（2019）

引用 13|浏览16

暂无评分

摘要

•Drug induced liver injury is a major reason for compound drop-out during drug development.•Xenopus embryos provide a useful in vivo model to study drug toxicity.•Xenopus embryos exhibit similar reactions to paracetamol induced liver injury observed in mammalian models.

查看译文

关键词

Xenopus laevis,Drug-induced liver injury (DILI),Paracetamol,Pre-clinical studies

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要