Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana.

Susan A Damanka,Chantal A Agbemabiese,Belinda L Lartey,Francis E Dennis, Frederick K Asamoah,Theophilus K Adiku,Christabel C Enweronu-Laryea,Kwamena W Sagoe,Michael F Ofori,George E Armah

PEDIATRIC INFECTIOUS DISEASE JOURNAL（2018）

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摘要

We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay-positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.

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Ghana,Group A rotaviruses,G2 genotype,Phylogenetic analysis

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