Brain mechanisms mediating effects of stress on reward sensitivity.

Current Opinion in Behavioral Sciences(2018)

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摘要
•Stress preferentially perturbates reward anticipation (rather than consumption).•Cortico–striatal–limbic network dysregulation subserves stress effects on reward.•Probing functional connectivity may allow greater cross-species integration.•Stress effects on opioid receptors may uncover novel treatment targets.
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关键词
Anhedonia,Corticostriatal Pathways,Depression,Dopamine,Early Life Stress,Motivation,Reward,Sensitization
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