Mathematical Modelling of a Hypoxia-regulated Oncolytic Virus Delivered by Tumour-associated Macrophages.

Journal of Theoretical Biology(2019)

引用 17|浏览10
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摘要
•A continuum model of macrophages releasing an oncolytic virus within a tumour spheroid.•Predictive modelling of this treatment given in combination with radiotherapy.•Investigation into how radiotherapy and oncolytic virotherapy should be scheduled.
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关键词
Mathematical modelling,Theory of mixtures,Oncolytic adenovirus,Tumour-associated macrophages
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