COA-Cl induces dopamine release and tyrosine hydroxylase phosphorylation: In vivo reverse microdialysis and in vitro analysis.

Mostofa Jamal,Ikuko Tsukamoto,Maki Takata,Asuka Ito,Naoko Tanaka,Takanori Miki,Ayaka Takakura,Kiyoshi Ameno,Yasuo Kubota,Ryoji Konishi,Hiroshi Kinoshita

Brain Research（2019）

引用 4|浏览23

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摘要

•COA-Cl produced a robust increase in extracellular DA in vivo. COA-Cl stimulated DA release in association with increased Ser31 and Ser40 phosphorylation.•Further, COA-Cl significantly induced neurite outgrowth.

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关键词

COA-Cl,Dopamine,Tyrosine hydroxylase phosphorylation,PC12 cells,iCell neurons,Mouse dorsal striatum

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