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Prognostic significance of interferon regulating factor 4 in esophageal squamous cell carcinoma.

Biochemical and Biophysical Research Communications(2018)

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摘要
•Increased expression of IRF4 is closely related to improved ESCC outcome.•IRF4 serve as an independent predictor of a positive prognosis in ESCC patients.•IRF4 may represent a promising prognostic biomarker and potential immuno-therapeutic target for ESCC patients.
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关键词
IRF4,Cancer,Esophageal squamous cell carcinoma,Tumor-infiltrating lymphocytes (TILs),Survival,Prognosis,Biomarker
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