Functional Mixed-Effects Modeling Of Longitudinal Duchenne Muscular Dystrophy Electrical Impedance Myography Data Using State-Space Approach.

Kush Kapur,Benjamin Sanchez,Adam Pacheck,Basil Darras,Seward B Rutkove, Rajesh Selukar

IEEE Transactions on Biomedical Engineering（2019）

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摘要

Objective: Electrical impedance myography (EIM) is a quantitative and objective tool to evaluate muscle status. EIM offers the possibility to replace conventional physical functioning scores or quality of life measures, which depend on patient cooperation and mood. Methods: Here, we propose a functional mixed-effects model using a state-space approach to describe the response trajectories of EIM d...

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关键词

Muscles,Biomedical measurement,Smoothing methods,Diseases,Splines (mathematics),Data models,Impedance

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