Effects of Thyroid Hormone Disruption on the Ontogenetic Expression of Thyroid Hormone Signaling Genes in Developing Zebrafish (Danio rerio).

Kyla M Walter,Galen W Miller,Xiaopeng Chen,Bianca Yaghoobi,Birgit Puschner,Pamela J Lein

General and Comparative Endocrinology（2019）

引用 36|浏览8

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摘要

•TH signaling genes are upregulated coordinately with larval zebrafish TH production.•Treatment with T4 or T3 both regulate transcription of TH-responsive genes.•Deiodinase 3b is sensitive to developmental hyperthyroidism and hypothyroidism.

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关键词

Endocrine disruption,Thyroid hormone,Transcriptomics,Zebrafish

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