Increased urinary exosomal microRNAs in children with idiopathic nephrotic syndrome.

EBioMedicine(2019)

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摘要
We identified 5 altered urinary exosomal miRNAs in NS children with disease progression and treatment. These urinary exosomal miRNAs could be promising and non-invasive potential biomarker candidates for diagnosing, monitoring and stratifying paediatric NS. FUND: National Natural Science Foundation of China; Fund of State Key Laboratory of Analytical Chemistry for Life Science; National Basic Research Programme of China; Foundation of Jiangsu Provincial Medical Youth Talent.
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关键词
Paediatric idiopathic nephrotic syndrome,Urinary exosomes,microRNA,Biomarker,Illumina sequencing via synthesis,RT-qPCR
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