Osthole decreases tau protein phosphorylation via PI3K/AKT/GSK-3β signaling pathway in Alzheimer's disease.

Yingjia Yao,Yameng Wang,Liang Kong,Yuqing Chen,Jingxian Yang

Life Sciences（2019）

引用 47|浏览3

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摘要

Taken together, the results indicated that OST could decrease phosphorylated tau levels via activation of PI3K/Akt/GSK-3β signaling pathway. Thus, this study demonstrated that OST might be a potential candidate for the treatment of AD.

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关键词

Alzheimer's disease,Phosphorylated tau protein,Apoptosis,PI3K,Osthole

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