Implications of Clinical Mycophenolate Mofetil Dose According to Individual Body Weight in Japanese Renal Transplant Recipients.
Transplantation Proceedings(2016)
摘要
•Body weight affects the MPA AUC:MMF dose ratio.•We need to consider individual body weight when deciding the MMF dose.•The MMF dose:body weight ratios can be index to predict MPA AUC without therapeutic drug monitoring.•A MMF dose:body weight ratio of 10–16 mg/kg predicts an MPA AUC between 30 and 60 μg·h/mL with a probability of approximately 75%.
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