A Gα-Stimulated RapGEF Is a Receptor-Proximal Regulator of Dictyostelium Chemotaxis

Developmental Cell, pp. 458-472, 2016.

Cited by: 0|Bibtex|Views9|DOI:https://doi.org/10.1016/j.devcel.2016.05.001
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Other Links: pubmed.ncbi.nlm.nih.gov|academic.microsoft.com|www.sciencedirect.com

Abstract:

Chemotaxis, or directional movement toward extracellular chemical gradients, is an important property of cells that is mediated through G-protein-coupled receptors (GPCRs). Although many chemotaxis pathways downstream of Gβγ have been identified, few Gα effectors are known. Gα effectors are of particular importance because they allow the ...More

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