Function and clinical meaningfulness of treatments for mild Alzheimer's disease.

Eric Siemers,Karen Chilcott Holdridge,Karen L Sundell,Hong Liu-Seifert

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring（2016）

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摘要

Function as the sole measure to demonstrate clinical meaningfulness of cognitive effects in mild AD may have limitations. For disease-modifying treatments, point differences on cognitive and functional scales should be qualified with duration of treatment.

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关键词

Solanezumab,Alzheimer's disease,Clinical relevance,Functional rating scales,Cognitive rating scales,Global rating scales,Mild cognitive impairment,Clinical meaningfulness

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