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Oxidative stress, genotoxicity and cytotoxicity of 1-methyl-3-octylimidazolium chloride on Paramisgurnus dabryanus.

Environmental Toxicology and Pharmacology(2016)

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摘要
•Acute toxicity test result showed that [C8mim]Cl had higher toxicity effect to P. dabryanus.•Biochemical analysis results showed that [C8mim]Cl could induce oxidative stress in fish.•Comet assay results showed that [C8mim]Cl induced obvious genotoxicity in fish.•Apoptosis analysis results showed that [C8mim]Cl induced obvious cytotoxicity in fish.•Toxicity effects of [C8mim]Cl to fish were obvious dose-t and time-effect relationships.
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关键词
Paramisgurnus dabryanus,[C8mim]Cl,Antioxidant enzymes,Comet assay,Apoptosis
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