Rosuvastatin safety: An experimental study of myotoxic effects and mitochondrial alterations in rats.

Samar O El-Ganainy,Ahmed El-Mallah,Dina Abdallah,Mahmoud M Khattab,Mahmoud M Mohy El-Din,Aiman S El-Khatib

Toxicology Letters（2017）

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摘要

•Atorvastatin and rosuvastatin induced myotoxic symptoms in rats.•Rosuvastatin had slight myotoxic manifestations compared to atorvastatin.•Effect of atorvastatin on mitochondrial functions was more evident than rosuvastatin.

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OATP,CK,LDH

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