When Clinical Trial Participation Is Not An Option In The Era Of Personalized Medicine: The Case Of Two Patients

Claire F Verschraegen, Hibba Rehman,Bhargavi Pulluri, James DeKay,Maura Barry, Edmund Folefac,Kim Dittus,Chris Holmes,Julian Sprague,Steve Ades,Pam C Gibson

ONCOLOGY（2017）

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摘要

The combination of personalized therapy with immunotherapy might lead to rapid complete remission in patients who are too sick to be eligible for clinical trials. We report 2 such extraordinary responders. A discussion on the use and purpose of clinical trials in this new era of very active anticancer drug discovery concludes that a paradigm shift is urgently needed. (C) 2016 S. Karger AG, Basel

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关键词

Targeted therapy, Immunotherapy, Clinical trials, Anticancer drug activity

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