Potentiation of the Fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida .

MedChemComm(2016)

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摘要
A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the surrogate . From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the sub-species and .
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