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[Successful treatment of severe dabigatran intoxication with idarucizumab in a patient with acute kidney injury].

Christina Gjerlev Poulsen, Morten Bestle, Lene Boesby

Ugeskrift for laeger(2017)

引用 23|浏览6
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摘要
In the course of an uncomplicated sigmoidostomy a 63-year-old male who had severe comorbidity developed a critical bleeding due to dabigatran intoxication induced by acute kidney injury. Massive blood transfusions, tranexamic acid, Octaplex and haemodialysis were not effective. Administration of idarucizumab induced immediate clinical and paraclinical improvement. Dabigatran should be carefully administrated in patients who have any degree of renal insufficiency. Idarucizumab may be effective in severe bleeding caused by dabigatran.
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关键词
severe dabigatran intoxication,acute kidney injury,idarucizumab,successful treatment
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