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Prevention of Arrhythmia Device Infection Trial: The PADIT Trial.

Andrew D Krahn,Yves Longtin,François Philippon,David H Birnie,Jaimie Manlucu,Paul Angaran,Claus Rinne,Benoit Coutu,R Aaron Low,Vidal Essebag,Carlos Morillo,Damian Redfearn,Satish Toal,Giuliano Becker,Michel Degrâce,Bernard Thibault,Eugene Crystal,Stanley Tung,John LeMaitre,Omar Sultan,Matthew Bennett,Jamil Bashir,Felix Ayala-Paredes,Philippe Gervais,Leon Rioux,Martin E W Hemels,Leon H R Bouwels, Bob van Vlies,Jia Wang,Derek V Exner,Paul Dorian,Ratika Parkash,Marco Alings,Stuart J Connolly

Journal of the American College of Cardiology（2018）

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摘要
The cluster crossover design efficiently tested clinical effectiveness of incremental antibiotics to reduce device infection. Device infection rates were low. The observed difference in infection rates was not statistically significant. (Prevention of Arrhythmia Device Infection Trial [PADIT Pilot] [PADIT]; NCT01002911).
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关键词
antibiotics,implantable cardioverter defibrillator,infection,pacemaker,prophylaxis
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