CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice.
Molecular Metabolism(2019)
摘要
•Long-acting FKN-Fc reduced atherosclerosis in LDLR KO mice in a prevention model.•FKN-Fc administration accelerated diet-induced regression of established atherosclerosis.•Monocyte adhesion in vitro and in vivo is reduced in the presence of FKN-Fc.
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关键词
Fractalkine,CX3CR1,Atherosclerosis,Monocyte adhesion,Inflammation,Ldlr KO
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