Voided Volume < 150 Ml On Initial Uroflowmetry In Men With Storage Symptoms: Is It An Unreliable Test Result Or A Sign Of Severe Storage Symptoms?

PLOS ONE(2019)

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摘要
PurposeTo assess the utility of voided volume on initial uroflowmetry in predicting symptom severity in men with storage symptoms. In addition, we assessed the probability that men would show a voided volume of >= 150 mL on uroflowmetry if the examination is repeated.MethodsBetween 2016 and 2017, 352 men with storage symptoms were enrolled in the study. The patients completed the frequency-volume chart and were divided into four groups based on the voided volume. A multivariate analysis was performed to determine the variables affecting voided volume.ResultsThe VV was < 68.8 mL in 88 patients (25.0%), 68.9-150 in 89 (25.3%), 150-250 in 87 (24.7%), and >= 250 in 88 (25.0%) patients. Although the International Prostate Symptom Score did not differ among the groups, the storage subscore was significantly higher in patients with decreased voided volume (p = 0.010). The total number of voids was greater in patients with decreased voided volume (p < 0.001), as was the number of nocturnal voids (p = 0.007). The maximum voided volume (p < 0.001) and 24-h urine output (p = 0.003) decreased as voided volume decreased. The proportions of patients with a mean daytime urine output >= 150 mL were 30.1%, 43.0%, 64.7%, and 66.7% in each group, respectively (p < 0.001). Older age and decreased maximum voided volume significantly affected the voided volume on initial uroflowmetry.ConclusionsA decreased voided volume on initial uroflowmetry may be a sign of severe storage symptoms in men. This finding is related to older age and decreased functional capacity. In these patients, it is better to perform a careful clinical assessment to diagnose and treat overactive bladder.
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