Ailanthone inhibits cell growth and migration of cisplatin resistant bladder cancer cells through down-regulation of Nrf2, YAP, and c-Myc expression

Marie Angele Cucci
Marie Angele Cucci
Margherita Grattarola
Margherita Grattarola
Benedetta Ferrara
Benedetta Ferrara

Phytomedicine : international journal of phytotherapy and phytopharmacology, Volume 56, 2018, Pages 156-164.

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Keywords:
AilanthoneBladder cancerC-MycCDDP-resistanceNrf2More(1+)

Abstract:

Aila inhibited proliferation and invasiveness of bladder cancer cells. Its high effectiveness in CDDP resistant cells could be related to the inhibition of Nrf2, YAP, and c-Myc expressions. Aila could represent a new tool to treating CDDP-resistant bladder cancers.

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