Maternal-Induced Shifts in Allostatic Demands: Reproductive Experience Alters Emotional and Cognitive Biobehavioral Responses in Rats (Rattus norvegicus).

Emily D K Sullivan,Molly Kent,Brooke Thompson, Massi Bardi,Kelly Lambert

Neuroscience Letters（2019）

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摘要

•Primiparous animals exhibited more on-task responses in the Dry Land Maze probe trial.•Primiparous rats responded to the uncertain probe trial with higher DHEA/corticosterone metabolites.•Nulliparous rats had higher glucocorticoid receptor- and lower BDNF-positive cells in the hippocampus.•In general, the primiparous females exhibited more efficient stress responses than nulliparous females.

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关键词

Primiparous,Nulliparous,Emotional resilience,Corticosterone,DHEA,Allostasis,Glucocorticoid receptor,BDNF

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